Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%
Lithium
42.82
0.85%
Gold
2,757.40
0.83%
Copper
4.39
0.62%
Oil
71.90
2%
Bitcoin
67,579.31
0.33%
FTSE 100
8,308.85
(0.11%)
Nikkei 225
38,411.96
(1.34%)
Dow Jones
42,800.62
(0.18%)
Iron Ore
100.70
(1.08%)
USD/AUD
0.67
0.28%
Hang Seng
20,498.95
0.32%

Paradigm Biopharmaceuticals (ASX: $PAR) revises protocol for phase 3 clinical trial

Paradigm Biopharmaceuticals' Strategic Update


Paradigm Biopharmaceuticals (ASX:PAR) has announced its plan to submit a revised protocol to the U.S. FDA by October 2024 for its Phase 3 clinical trial. This trial focuses on the injectable pentosan polysulfate sodium (iPPS) for osteoarthritis treatment. The company anticipates beginning patient enrolment in early 2025.

Paradigm's Strategic Focus and Future Plans


Paradigm Biopharmaceuticals is advancing with a revised Phase 3 clinical trial protocol for iPPS, addressing FDA feedback to improve trial efficiency. Patient enrolment is expected to commence in early 2025. The company is in the process of selecting a CRO from four shortlisted global contenders. Governance updates include Dr. Donna Skerrett focusing on her CMO duties, while the board ensures independent oversight. The company demonstrates investor confidence through board share purchases and explores shareholder rewards if PARO options expire. Paradigm remains dedicated to developing treatments for inflammation-driven diseases.

Executive Insights on Revised Protocol


The revised protocol incorporates feedback from the FDA aimed at enhancing patient convenience, improving retention, and reducing trial costs. We remain confident in our progress and strategic direction.

PARADIGM BIOPHARMACEUTICALS LIMITED..
PAR | ASX | Health Care
0.215-0.01(-4.44%)
At close 21/10 (AEDT)
Market cap
$75.3M
Volume
1,606,811
DY Yield
PE Ratio
52 Week Range
0.165 - 0.641951
1YR Return
N / A

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