In the intricate tapestry of neurological research, Xanamem emerges as a beacon of hope, offering a transformative once-a-day treatment with a unique, non-amyloid/non-tau mechanism. Developed by Actinogen Medical, Xanamem is a brain-penetrant 11β-HSD1 small molecule enzyme inhibitor designed to reduce brain cortisol, presenting a novel approach to addressing cognitive challenges. The potential of Xanamem extends beyond its innovative mechanism, showcasing promising attributes: Rapid Cognitive Enhancement: Xanamem holds the promise of rapidly enhancing cognitive function, providing a potential breakthrough for individuals grappling with neurological disorders. Disease-Modifying Effects: With the potential to slow down disease progression, Xanamem emerges not only as a symptomatic treatment but also as a transformative option with disease-modifying capabilities. Antidepressant and Anti-Inflammatory Effects: Xanamem's multifaceted approach includes antidepressant and anti-inflammatory effects, addressing the intricate interplay between mental health and inflammation. Insulin Sensitizing: Offering benefits beyond the neurological realm, Xanamem demonstrates insulin-sensitizing properties, hinting at its potential impact on metabolic health.